Iron Deficit Calculator (Ganzoni)

Find the total iron deficit (Ganzoni).

How it is calculated

Enter body weight in kilograms, the patient's current haemoglobin and the target haemoglobin, both in g/dL. The tool applies the Ganzoni formula: deficit (mg) = weight × (target Hb − actual Hb) × 2.4 + 500. The product of the first three terms is the iron needed to rebuild haemoglobin, and the added 500 mg stands for iron stores.

The stores amount is always 500 mg in this tool, whatever the weight. Some references use a different stores figure for children or low body weight, so for those patients the clinician's own value should replace it. The target must be higher than the actual value, and weight must be above zero, or there is no result. The answer is in mg with two decimals. It is a calculation aid only and not a dosing instruction.

Worked example

A 70 kg adult with haemoglobin 9 g/dL and a target of 15 g/dL. The gap is 15 − 9 = 6 g/dL. Haemoglobin part: 70 × 6 × 2.4 = 1,008 mg. Add 500 mg for stores: 1,008 + 500 = 1,508.00 mg. A 20 kg patient with the same haemoglobin values gets 20 × 6 × 2.4 + 500 = 788.00 mg.

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Common mistakes

  • Entering haemoglobin in g/L (for example 90 instead of 9). The factor 2.4 is built for g/dL, so g/L inputs overstate the deficit about tenfold.
  • Entering weight in pounds. The formula needs kilograms.
  • Swapping the target and actual values. The target must be higher than the actual one; if it is not, the tool shows nothing.
  • Assuming the 500 mg stores term adjusts for children or small adults. Here it is constant, so the result for a light patient may need a clinician's adjustment.
  • Reading the result as a prescription. Dosing, product choice and the number of infusions depend on the clinician and on the drug used.

About this calculator

The Ganzoni formula estimates total body iron deficit in milligrams: deficit = weight(kg) × (target Hb − actual Hb, in g/dL) × 2.4 + iron stores. This calculator always adds a fixed 500 mg, the usual figure for adults of 35 kg or more; references use 15 mg/kg for children and lighter adults, so the result does not fit them as is. The factor 2.4 converts the haemoglobin gap into the iron mass needed to rebuild red-cell haemoglobin, and the added store term accounts for replenishing the body's iron reserves, not just the blood itself.

Haematologists, nephrologists managing dialysis patients, and gastroenterologists treating iron-deficiency anaemia from chronic blood loss use this calculation to size a course of intravenous iron replacement, since oral iron is often too slow or poorly tolerated for larger deficits. It is a calculation tool only — the resulting figure is meant to inform a clinician's decision, not to be interpreted as a treatment recommendation.

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