Fractional Excretion of Sodium Calculator

Enter urine and plasma sodium and creatinine to compute FENa.

How it is calculated

The tool compares how much sodium reaches the urine with how much creatinine does: FENa % = (urine Na × plasma Cr) ÷ (plasma Na × urine Cr) × 100. Sodium is entered in mmol/L (mEq/L) and creatinine in mg/dL, using the same unit for the urine and plasma value of each substance; only the ratios matter, so each pair just has to match. Besides FENa the tool shows two ratios, urine Na ÷ plasma Na and urine Cr ÷ plasma Cr. Accepted ranges: urine sodium 0 to 500, plasma sodium 80 to 200, and both creatinine values above zero. Anything outside these ranges, or a FENa that would come out above 100 %, shows no result. The tool only calculates the figure. In the usual teaching, below 1 % points toward a prerenal cause and above 2 % toward tubular damage, with the range between unclear, and diuretics or other factors can distort it.

Worked example

Spot urine sodium is 20 mmol/L, plasma sodium 140 mmol/L, urine creatinine 90 mg/dL and plasma creatinine 2.1 mg/dL. Sodium ratio = 20 ÷ 140 = 0.14. Creatinine ratio = 90 ÷ 2.1 = 42.86. FENa = 0.14286 ÷ 42.86 × 100 = 0.33%. This is a low value, and by the usual rule of thumb below 1 % fits a kidney that is conserving sodium, as seen in prerenal conditions. A clinician interprets it alongside the rest of the picture.

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Common mistakes

  • Mixing units inside a pair, such as urine creatinine in mg/dL and plasma creatinine in µmol/L. The ratio is then wrong by a factor of about 88.
  • Swapping urine and plasma values. The formula is not symmetric, so the result can be far off, and a swap can push FENa above 100 %, which gives no result.
  • Using FENa after diuretics without caution. The drug raises sodium excretion and can hide a prerenal picture. This is a known limitation, not an error in the arithmetic.
  • Reading the percentage as the amount of sodium lost. It is the share of filtered sodium that is excreted, not grams or millimoles per day.
  • Entering sodium in the creatinine box or the reverse. The order is urine Na, plasma Na, urine Cr, plasma Cr, and a plasma sodium below 80 or above 200 shows no result, which usually signals a mix-up.

About this calculator

Fractional excretion of sodium (FENa) measures what percentage of the sodium filtered by the kidneys actually ends up in the urine, calculated as FENa = (urine sodium × plasma creatinine) ÷ (plasma sodium × urine creatinine) × 100. Creatinine appears in the formula as a reference marker because it's freely filtered and barely reabsorbed, which lets the ratio cancel out urine concentration effects and isolate how much sodium the kidneys are actively reabsorbing versus excreting.

Nephrologists and emergency physicians use FENa to distinguish prerenal azotemia (kidneys are healthy but underperfused, so they aggressively reabsorb sodium, giving FENa less than 1%) from acute tubular necrosis (the tubules themselves are damaged and can't reabsorb sodium properly, giving FENa greater than 2%) in a patient with acute kidney injury — a distinction that changes treatment, since prerenal causes respond to fluids while ATN does not.

This calculator takes urine and plasma sodium and creatinine values and returns the calculated FENa.

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